Objective To investigate the status of dyadic coping in young and middle-aged type 2 diabetes patients,and to explore the influencing factors. Methods A total of 411 young and middle-aged type 2 diabetes patients were recruited from 2 tertiary hospitals in Zhengzhou from February to December 2020,and they were investigated with a general information questionnaire,Dyadic Coping Inventory(DCI) and Diabetes Self-efficacy Scale(DSES). Results The total DCI score was 130.60±11.26 and the total DSES score was 93.11±18.93,showing significantly positive correlation(r=0.323,P<0.05). Gender,duration of disease,family monthly income and self-efficacy were main factors affecting dyadic coping of patients(P<0.05 for all). Conclusion The level of dyadic coping in type 2 diabetes patients are average and needs to be further improved. Self-efficacy can be used as the starting point to develop feasible and effective interventions to enhance dyadic coping of patients with type 2 diabetes in clinical nursing.